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In the SURPASS clinical trial programme, heart rate increases were documented with mean increases ranging from 1.4 to 4.6 beats per minute across different doses (5 mg, 10 mg, and 15 mg weekly) compared to baseline
Current Pharmaceutical Design , 2020 2
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Additional potential benefits include berberine's reported effects on lipid profiles, with some studies suggesting reductions in LDL cholesterol and triglycerides, though evidence is of low-to-moderate certainty with heterogeneous results
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