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We merged genes from the three databases to create a gene set for each pathway (Additional file 1: Tables S2S4), resulting in 5325, 2557, and 3435 genes for Most Studied Pathways, Gene-Associated Pathways, and Popular Pathways, respectively

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The cancers included breast cancer, liver cancer, colorectal cancer, and non-small cell lung cancer

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Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndrome