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One preclinical treatment study in tauopathy mice reported anti-inflammatory or neuroprotective effects mediated by the Nrf2/antioxidant response element (ARE)

For context: a single jar of high-end topical copper peptide serum costs $60-150 and lasts a month

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the BDNF paradox (SSRIs generally raise BDNF and hippocampal neurogenesis via 5-HT1A/5-HT4 signalling, so antidepressant fog is not a synapse-deficiency a peptide refills)

It also helps to correct severe deficiencies very quickly (if the deficiency is not based on genetic abnormalities which may require a specific form(s) of B12)