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A standout example is tirzepatide, a co-agonist at the receptors for GLP-1 and GIP

17 In their typical form, they have a well-demarcated, plaque-like profile (appearing stuck-on')

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Generally, for medications like Wegovy and Zepbound, which are approved for weight management, individuals must have a Body Mass Index (BMI) of 30 kg/m or greater (considered obese), or a BMI of 27 kg/m or greater (considered overweight) along with at least one weight-related comorbidity such as high blood pressure, type 2 diabetes, or high cholesterol

10 Liraglutide was generally well tolerated