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Possible Side Effects Observed in Research Settings Semaglutide has been explored in laboratory and experimental research settings, and observed responses in some research contexts have included: Nausea Gastrointestinal discomfort Reduced appetite-related observations Vomiting Diarrhea or constipation Bloating or abdominal discomfort Fatigue or lethargy Headaches Injection-site irritation or redness Gastrointestinal & Administration Considerations In some research models, more significant gastrointestinal-related observations have been reported during higher-exposure or administration-escalation protocols
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Second, the heterogeneity of included studies was high
It makes you puffy
Even in strict vegetarian diets (as little as 1 mg/day exogenous carnitine for a 70 kg person), endogenous synthesis combined with the high tubular reabsorption rate is enough to prevent deficiency in generally healthy people
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