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Orlistat (Xenical/Alli), a lipase inhibitor available on the NHS, typically produces mean weight loss of around 35% compared with placebo over 12 months, making it a modest option for many patients

The headline result was a mean 17.5% body-weight reduction at 24 weeks in the 12 mg arm, with clear dose-response behavior across the four active doses

Front Mol Biosci 12: 1622186

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Clinical practice guidelines for weight management in postpartum women: An AIIMS-DST initiative in association with FOGSI