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The B -factors of the crystal structures were calculated by Baverage 53 , and the volumes of the protein cavities were calculated using the CASTp server 54 with a probe radius of 1.4

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IGF-1 Des (des(13) insulin-like growth factor-1) is a truncated IGF-I analog that exhibits lower affinity for the IGF binding proteins and higher diabetogenic, mitogenic activity than native IGF-1

For example, separate calcium and iron supplements

To further dissect the molecular mechanism underlying GLUD1 degradation via the proteasomal pathway, we sought to identify the mediator(s) that govern the ubiquitin-dependent degradation of GLUD1 under conditions where GLUD1 methylation is abrogated

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