Kregel, K
The tradeoffs are different Metformin Usually inexpensive and available as a generic Often causes diarrhea, nausea, or stomach discomfort at first Extended-release formulations may be easier to tolerate May require vitamin B12 monitoring with long-term use Has much more pregnancy-related clinical experience than newer GLP-1 medicines GLP-1 or GIP/GLP-1 medicines Can substantially reduce appetite and weight in eligible patients Commonly cause nausea, constipation, reflux, or diarrhea May make it difficult to eat enough protein, fiber, and micronutrients Can be expensive or difficult to access consistently Are not recommended during pregnancy and require a preconception plan Often require long-term treatment to maintain the full effect Can they be used together
However, when glutathione was added, there was a steep decrease in the percentage of oxyhemoglobin as a result of the pro-oxidation effect of glutathione
Both medications can contribute to fluid and electrolyte imbalances, with sertraline specifically associated with hyponatremia risk, particularly in older adults
Circulation 104, 346351
The olfactory acuity is regulated by the metabolic state and therefore the olfactory system is a driver of feeding behavior
