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Engineers and researchers at MIT Lincoln Laboratory, defense and aerospace teams around Hanscom Field, and the software and biotech companies lining the Route 128 corridor all share the same complaint: mental fatigue that builds up faster than a weekend can clear it
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This is due to the absence of ClpL chaperone function or a decrease in Mn 2+ levels, which negatively affects both SodA and ClpL since their enzymatic activities rely on Mn +2 levels (Reinoso-Vizcaino et al., 2020
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