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When assessing for vitamin B12 deficiency, in addition to checking a vitamin B12 level, consider ordering a methylmalonic acid level or a holotranscobalamin level and CBC (to assess for red blood cell size)
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In parallel, studies have reported modulation of early growth response-1 (EGR-1) expression and its regulatory partner NAB2, which are involved in cytokine signaling and early extracellular matrix formation during cellular response processes [2]
Aug 4 2016;6:31166
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