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Optimizing the substituent on the benzimidazole nitrogen proved a fruitful approach to improve potency without detrimentally impacting physiochemical properties, with smaller, more polar groups preferred
Unlike oral administered, which can cause stomach upset, intravenous offers a preferable option for minimizing discomfort without gastrointestinal side effects
In that study, platelet aggregation was found to be significantly lower in patients treated with ticlopidine and EGb 761 as compared with patients treated with ticlopidine alone (Hong et al., 2013)
Please visit Ozempic.com or Wegovy.com for a full list of important safety information for these medications
Specific concerns related to GLP1 receptor agonists can be broadly classified into the following categories: side effects/safety, access, and medication adherence