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Journal reference: Xie Y, Choi T, Al-Aly Z (2026)

The landmark SURMOUNT-OSA trial found that tirzepatide reduced the apnea-hypopnea index (AHI), the standard measure of sleep apnea severity, by approximately 50 to 60 percent at 52 weeks (Malhotra et al., New England Journal of Medicine , 2024)

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