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The hints of benefit were enough to spark real hope
By lowering systemic inflammation throughout the body, these drugs potentially counteract one of the primary drivers of dementia development
Journal Reference : Javier Bracchiglione, Nicols Meza, Juan VA Franco, Camila Micaela Escobar Liquitay, Victoria Novik A, Miranda Ocara Vargas, Gabriel Lazcano, Daniel Poloni, Francisca Rinaldi Langlotz, Marta Roqu-Figuls, Sergio R Munoz, Eva Madrid
showed that topical glutathionecyclodextrin (GSH-CD) increased intracellular GSH in mononuclear and red blood cells, decreased malondialdehyde (MDA), and significantly upregulated immune cytokines including IL-2, IFN-, IL-12p70, and TNF-
In response to 5FU treatment, we see little to no impact on other nucleotide families (apart from ATP as previously shown
PMID 37370556
