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When this pathway breaks down it causes increased levels of oxidative stress within the cell that leads to glutathione depletion and mitochondrial dysfunction (49)

Novo Nordisks new oral GLP-1, Wegovy pill, is a once-daily pill offering comparable weight-loss results (an average of 13.6% of your body weight) to injectable Wegovy.^ ^Eligible patients lost an average of 13.6% of their body weight in a 64-week clinical trial evaluating 25 mg oral semaglutide compared to those on 2.4 mg injectable semaglutide who lost an average of 14.9% of their body weight in a 68-week clinical trial

Promotion of Satiety By acting on the hypothalamus and other areas of the brain, GLP-1 reduces appetite and promotes feelings of fullness

Gila monsters seldom hunt, but when they do, they are capable of inflicting serious punishment

Ghusn and Hurtado, 2024)

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