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doi:10.1016/j.neuroimage.2013.01.045 104a
Introduction In patients with T2DM, the incretin effect is reduced or in some cases, absent [1]
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Intervention with ferroptosis inhibitors such as ferrostatin-1 and deferoxamine has been shown to restore chondrocyte viability, reduce MMP13 and ADAMTS5 expression, and partially rescue extracellular matrix loss, suggesting that inhibiting ferroptosis may mitigate OA cartilage injury (54, 55)
Contrary to this, using weight loss medications encourages a lower appetite, and in turn, less calorie intake throughout the day
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