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2730 Studies have shown that GLP-1RAs can inhibit carotid body chemoreceptor activity, reducing sympathetic nervous system outflow

BCKDK phosphorylates the E1 subunit at Ser293 to inactivate it, while PPM1K dephosphorylates to activate BCKDH (125)

Nausea, vomiting, and diarrhoeareported by a substantial proportion of patients, especially during treatment initiationresult in the loss of not only water but also essential electrolytes, particularly sodium, potassium, and chloride