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The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting
Methylmalonic acid (MMA) test: Methylmalonic acid test detects elevated levels of MMA, a compound that increases when there is a deficiency of vitamin B12
Downsides to potential peptides ban Why you should care: If the FDA enforces a strict ban, patients managing conditions like colitis, depression, severe inflammation, and sleep disorders through custom peptide therapies could lose access to their treatments overnight
Oudart J-B, Villemin M, Brassart B, Sellier C, Terryn C, Dupont-Deshorgue A, Monboisse JC, Maquart F-X, Ramont L et al (2021) F4, a collagen XIX-derived peptide, inhibits tumor angiogenesis through v3 and 51 integrin interaction
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