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(6) Increased bone marrow adipose tissue accumulation and altered mesenchymal stem cell differentiation contribute to reduced osteoblast activity, increased osteoclastic resorption, and an overall decline in bone strength, leading to a greater fracture risk despite higher bone mineral density measurements

Front Nutr 11:1433390 Lisicki M, DOstilio K, Coppola G et al (2018) Brain correlates of single trial visual evoked potentials in migraine: more than meets the eye

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The honest caveat: most of this evidence is from cell and animal studies

Long-term studies