Methylcobalamin is the active form of Vitamin B12 and supports nerve cell repair, nerve regeneration, red blood cell formation, and myelin sheath maintenance
Up to 50% improvement in cognitive performance and mood-related symptoms has been reported in patients treated with B12 injections, especially in those with mild deficiency
20 In 2017, Paul and Brady came to similar conclusions that all four forms appear to be effective, although they point out research that shows that tissue retention of cyano-B12 is lower and urinary excretion higher than that of the other forms, although this statement is based on a review from 1965
This research has implications for understanding the regulation of NAD+-dependent processes in cells
The catch is that your body cant store these vitamins for later use, meaning you need a more frequent intake to ensure you arent deficient in water-soluble vitamins
While lipohypertrophy is well-documented with insulin therapy, it can also occur with GLP-1 receptor agonists like Saxenda, though less frequently