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However, adaptation may take longer during Wegovy's 16-week titration period, and individual tolerance varies considerably

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Given that GLP-1 biology is complex and may involve several parallel mechanisms with or without transmembrane receptors (31) and distinct metabolites (32), we chose to next focus on the direct actions of the single metabolite GLP-1(2836) using in-depth in vitro studies into its cellular and molecular actions

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Ultimately, balanced risk-benefit assessment supports effective and safe diabetes management

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