Triagonist-treated mice showed a slight reduction of body weight along treatment (2%) and improved glucose tolerance, although no changes were detected in the other metabolic parameters analyzed (Fig
However, this was an observational study, so it does not establish causality, and GLP-1 agents should not yet be considered primary treatments for depression or anxiety, he told Healthline
So, if you've been on your current dose of GLP-1 for at least a month and your weight has not decreased by a relevant amount, it's possible that you need to increase your dose to have an effective weight loss again
Important safety information: Retatrutide is an investigational medicine
By week 24, that figure was 19.5%
If constipation improves, those were contributing factors