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In 2020, it became the only diabetic drug to be approved for reducing or preventing the risk of major cardiovascular events (MACE) in patients with type 2 diabetes

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The reducing capacity of GSH is essential for regulating the redox environment, as it can reversibly form oxidized glutathione (GSSG) through the coupling of two GSH molecules

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Key Takeaway: GHK-Cu acts through multiple overlapping mechanisms fibroblast activation, controlled copper delivery, antioxidant signaling, and broad gene-expression modulation