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Moreover, a separate STEP UP sub-analysis presented at ECO shows that most of the weight loss with Wegovy was coming from body fat, and most of the muscle mass was kept
They: Increase insulin release when blood sugar rises Decrease glucagon, which helps prevent blood sugar spikes Slow gastric emptying, so food moves more gradually through the digestive tract Increase feelings of fullness and reduce appetite Signal in the brain to influence hunger, cravings, and reward Together, these effects change how your body processes food, regulates energy, and responds to hunger signals
These conditions can include type 2 diabetes, high blood pressure, dyslipidemia, obstructive sleep apnea, or non-alcoholic fatty liver disease
and Rafanelli, C
Br J Pharmacol (2020) 177(5):100324
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