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In contrast, GSTP1 promoter remains almost unmethylated in benign lesions, allowing distinguishing benign and cancerous transformations ( Lung cancer Leukemia and lymphoma Breast cancer Jhaveri and Morrow initially published that methylation status of GSTP1 promoter contributes significantly to the levels of GSTP1 expressed in ER-negative and ER+-positive breast cancer cell lines ( Liver cancer According to Zhang et al