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Similarly, in December 2023, Roche agreed to buy GLP-1RA drug developer Carmot Therapeutics for up to $3.1bn
Joji Suzuki, director of addiction psychiatry at Brigham and Womens Hospital in Boston, who is leading two clinical trials of GLP-1s for alcohol and opioid use disorders and is not involved in the Providence program
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2020;53(6):e12829
Human data are mostly limited to short-term interventions, and direct measurement of lysosomal activity or autophagic flux in clinical trials remains challenging due to the lack of standardized, non-invasive biomarkers [30]
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