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The results of this systematic review and meta-analysis demonstrate that glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce the risk of major adverse cardiovascular events (MACE)
Participants were randomized to once-weekly subcutaneous retatrutide 1 mg (n = 20), 4 mg (n = 19), 8 mg (n = 22), 12 mg (n = 18) or placebo (n = 19)
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The FDA expanded semaglutide's (Wegovy) use to reduce the risk of cardiovascular death, heart attack, or stroke in adults with cardiovascular disease and overweight or obesity, based on a cardiovascular outcomes trial in which it reduced major adverse cardiovascular events by 20% compared with placebo
Your doctor may give you insulin temporarily instead
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