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2024 Oct 1, Volume 195, Page 112522

The simple explanation is biology becomes better at healing, period

This means that a peptide with a 2-hour half-life administered three times daily will reach steady-state within approximately 10 hours, while a peptide with a 7-day half-life like Semaglutide requires roughly 35 days to reach steady state with weekly dosing

For medical professionals considering BPC-157 in clinical practice, current use must acknowledge the investigational nature of the peptide and proceed within appropriate ethical frameworks including informed consent, safety monitoring, and outcome documentation

It was discontinued in 2008 for manufacturing reasons, not safety concerns

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