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On the other hand, there was a significant increase in the levels of oxidized GSH (GSSG) in the plasma ( Figure 4I ), PBMCs ( Figure 4J ) and RBCs ( Figure 4K ) samples from individuals with T2DM at 3-months post-placebo supplementation

Iron-catalyzed lipid peroxidation, along with iron-catalyzed protein nitration, contributes to the induction of the mitochondrial permeability transition and cell necrosis