349,350 At the same time, the levels of two important components of the cartilage matrix, proteoglycans (a large molecule and a major component of the cartilage matrix) and type II collagen (the main structural protein of cartilage), increased
Other risk factors that may increase vulnerability include: Long duration of diabetes (typically more than 10 years) Poor glycaemic control prior to starting GLP-1 therapy (HbA1c significantly above target) Rapid reduction in HbA1c (a drop of more than 2 percentage points [22 mmol/mol] within 36 months) Concurrent hypertension , especially if poorly controlled Diabetic kidney disease (nephropathy), which often correlates with retinopathy severity Previous history of retinal treatment (laser photocoagulation or intravitreal injections) People with type 2 diabetes but no retinopathy appear to have minimal risk of retinopathy progression based on current evidence
Cervenka MC, Patton K, Eloyan A, Henry B, Kossoff EH
Delivery took a couple of days longer than expected, but the quality more than made up for it
Storage Storage & Stability BPC-157 is tougher than most peptides its gastric acid resistance gives it an edge in stability
A relatively unknown antioxidant, alpha-lipoic acid, may be more potent than vitamins C and E