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In the plasma-conditional culture experiments, the upregulated mRNA levels of Ins1 , Ins2 , Pcsk1 and Pdx1 in either Min6 cells or mouse islets induced by exposure to plasma of the GCGR mAb-treated mice were attenuated by addition of FGF21 nAb (Fig

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Choline prevents the hepatic fat accumulation that occurs when phospholipid synthesis can't keep pace with dietary fat intake

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These side effects are usually mild to moderate and tend to improve with time, but they can be uncomfortable to live with