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Optometrists should advise their patients that although these medications are conclusively linked to an increased risk of NAION, the overall risk is still extremely low: only about 2.30 per 100,000 people are diagnosed with NAION each year
The medications mimic it
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fda.gov (Mounjaro approval press release)
Getting too little sleep has been shown to increase visceral fat but, in young adults at least, so has too much sleep
The FOXO4 factor is considered to regulate various cell pathways, including insulin signaling, cell cycle progression, and other functions that regulate growth and differentiation
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