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However, under cellular conditions, the concentration (110 mM) of GSH is several folds higher than of hydroperoxides (10100 M), and thus, the velocity ( V max ) of the detoxification of hydroperoxides by seleno-GPxs is practically independent of the concentration of GSH [8, 17, 18]
Scientists derived this peptide from a larger protective protein found naturally in human gastric juice
Different populations of human locus ceruleus neurons contain heavy metals or hyperphosphorylated tau: implications for amyloid- and tau pathology in Alzheimers disease
10.1111/j.1749-6632.1998.tb09019.x Ann
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however, the GSH antioxidant system can be overwhelmed if ROS are produced in excess, leading to increased levels of free radicals that can damage molecules that are essential to cellular homeostasis and metabolism
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