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10.1515/DMDI.2008.23.1-2.51 Drug Metabol
Aug 2019;45:109-113
Indeed, in pre-clinical models, retatrutide, a triple agonist (GLP-1/GIP/glucagon), resulted in greater WL and improved glucose profile compared to tirzepatide through increased energy expenditure and reduced calorie intake [80, 81]
Fast-evolving model
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