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Urate-induced epigenetic modifications in myeloid cells

The underlying compounds are well studied GLP-1 receptor agonists such as semaglutide, liraglutide, and dulaglutide, and the dual agonist tirzepatide, examined in STEP ( NEJM , 2021), SURMOUNT (NEJM 2022), and SURMOUNT-OSA (NEJM 2024) but a legitimate program is defined by how responsibly it prescribes them, not merely that it offers them

But the official regulatory framework covers only the diabetes indication at this time