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Br J Haematol 145:4558

Role of glutathione and glutathione S-transferase in chlorambucil resistance [PMID: 1569917] Laboratory literature summary: Role of glutathione and glutathione S-transferase in chlorambucil resistance

However, physicians noticed these patients started losing weight when taking this medication

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Histamine-secreting bacteria were abundant in people with histamine intolerance.[ref] Another study found that people with histamine intolerance found that they had a much lower abundance of Bifidobacteria in the gut and higher levels of Proteobacteria and Roseburia species

This means that while the label might say 500mg, your body might only receive a tiny fraction of that amount