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Much of the reported 40% lean mass loss with GLP-1 use is coming from the liver, explained exercise physiologist Keith Baar, a professor of Neurobiology, Physiology and Behavior and Physiology and Membrane Biology

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Semaglutide improves overall metabolic health by enhancing insulin sensitivity and improving lipid profiles

They're experimental substances that have shown promise in animal studies but have never undergone proper human trials

The basis for the remaining ~50% of GLP-1 dependent LAG-1 accumulation is not known

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