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Participants in one trial lost around 15% of their body weight over 72 weeks, with many losing more than 20% at a higher dosage
Because it is an oral medication, it sometimes falls under a different insurance tier, making it a more affordable semaglutide option for some patients
The lower starting dose was specifically chosen based on phase 3 trial refinements to improve gastrointestinal tolerability compared to earlier, more rapid dose escalation schemes
It mimics a hormone your gut releases after eating signaling your brain that youre full, slowing stomach emptying, and reducing appetite
This is the same mechanism that causes vaginal atrophy during menopause, but in the context of semaglutide, it happens faster because the weight loss occurs over months rather than years
The semaglutide withdrawal symptoms guide covers this process in detail
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