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Moreover, mesoporous silica nanoparticles (bMSNs) carrying multiple neoantigen peptides, CpG oligonucleotide adjuvants, and photosensitizer chlorine e6 can not only efficiently accumulate in tumors but also recruit DCs to the tumor site of PDT treatment by combining laser irradiation with PDT and induce neoantigen-specific CTLs to exert strong anti-tumor immunity against locally treated tumors as well as distant untreated tumors (186)
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By targeting these general mechanisms, drugs can exert specific effects in definite diseases, repairing disrupted processes precisely where they occur
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