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Weight loss with GLP-1 therapy follows a predictable trajectory, though individual results vary based on starting point, consistency, and lifestyle factors

Individual results will vary based on factors including age, baseline weight, metabolic health, consistency of use, lifestyle factors, genetic factors, current medications, and other individual variables

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Trulicity comes as a subcutaneous injection that is given once a week

In the interim analysis of a phase III study (REGENERATE trial) at 18 months, 931 NASH patients with stage 23 fibrosis were randomly assigned to placebo and showed significant fibrosis improvement without NASH deterioration

Additionally, tirzepatide may cause fewer gastrointestinal side effects and provides extra benefits for patients with type 2 diabetes or increased cardiovascular risk, including improved glucose control and reduced cardiovascular event risk