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In the intensely competitive GLP-1 drug market, simply enhancing drug efficacy is no longer sufficient to make new products stand out

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He later described exendin-4 as the fifth child of our familya creation he nurtured despite all evidence that the world was not interested

In the pharmaceutical world, a patent gives a company the exclusive right to make and sell a drug for a set periodusually 20 years from the date of filing

"We think that some of these people may be changing behavior, nutrition, lifestyle, [and] also may be changing the hormones in their body by being on [GLP-1 medications], changing how their brain sort of operates or functions permanently," Narula said

We would also like to point out that hyperthyroidism can increase renal blood flow and glomerular filtration rate 39 , while kidney is thought to be a major site of GLP-1 extraction 40