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They are not associated with cardiovascular protection beyond glucose lowering, so they are typically chosen when GLP-1 agonists or SGLT2 inhibitors are unsuitable

[18] The function with domain [0,1] defined by for is convex

Moreover, because semaglutide is not yet approved for psoriasis, using it for this purpose would be considered an off-label use

Regul Pept 137(3):168172 Vrang N, Larsen PJ (2010) Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: role of peripherally secreted and centrally produced peptides

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