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Sources Nature Medicine: Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial PubMed: Tirzepatide Once Weekly for the Treatment of Obesity Cleveland Clinic Journal of Medicine: Tirzepatide adds significant weight loss even after lifestyle changes MedicalNewsToday: How to Travel with Zepbound FDA Label: MOUNJARO (Tirzepatide Injection) Medication Guide FDA Label: ZEPBOUND (Tirzepatide Injection) Medication Guide Important Medical Information and Disclaimers Important Current Status Update : On March 19, 2025, the FDA ended enforcement discretion for compounded tirzepatide