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Presented for research literature review only Hayes JD et al
The signaling pathways in the GIT includes the complex enteric nervous system (ENS) that consist of two neural networks located in the submucosa layer and has pacemaker cells and controls i.e., motility via release of neurotransmitters based on the amino acid tryptophan associated neurotransmitter serotonin (5-HT: Serotonin, 5-hydroxytryptamine), dopamine and GABA
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