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Ozone was first used as an antimicrobial agent in 1873, and in 1885 the first textbook on the medical application of ozone was published in 1885 by Dr

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Elevated levels of Lp(a) are a strong risk factor for having a heart attack due to atherosclerotic plaque buildup.[ref] Lipoproteins are fat-protein packages that transport cholesterol through the bloodstream, including LDL, HDL, and lipoprotein(a)