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Extra caution is appropriate in patients with active cancer, recent cancer, unexplained masses, unexplained weight loss, pregnancy, breastfeeding, known allergy to peptide products, active infection, immune compromise, significant liver or kidney disease, active inflammatory or autoimmune disease flares, unusual clotting history, uncontrolled cardiovascular disease, use of chemotherapy or immune-modifying biologic therapy, and competitive athletes subject to anti-doping rules

This includes choosing the appropriate injection site and rotating injection sites to avoid tissue damage or irritation

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But in most cases, no

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Studied for skin regeneration, hair follicle biology, anti-aging, and wound healing