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Nat Rev Neurosci 20(3):148160 Cai H-Y et al (2021) A GLP-1/GIP dual receptor agonist DA4-JC effectively attenuates cognitive impairment and pathology in the APP/PS1/Tau model of Alzheimers disease 1

Purities below 99% introduce receptor desensitisation artefacts from deletion-sequence and oxidation impurities