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While clinically relevant interactions have not been consistently demonstrated, caution is advised

Here's what the current materials actually show, including what's changed since earlier coverage and what's worth checking before you enroll

J Med Genet 40:619625 Wilson A, Platt R, Wu Q, Leclerc D, Christensen B, Yang H, Gravel RA, Rozen R (1999) A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida

A study published recently found that the use of metformin during the initial phases of a COVID-19 infection decreased the likelihood of developing Long COVID (Bramante et al., 2022)

Understanding how these treatments interact with oral contraceptives, emergency contraception, and fertility is vital if youre trying to avoid pregnancy or plan another one in the near future

More recently, theyve been approved for weight management in people who are overweight or obese