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Gut Dysbiosis Gut dysbiosis refers to an unhealthy or unbalanced gut microbiome

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Under a quiescent condition, HCK elaborate constituents contributing to the formation of an organized collagenous transparent framework stroma, but during exposure to various stresses or infection HCK can be induced to undergo transdifferentiation into fibroblasts and myofibroblasts

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A subsequent study indicated that liver organoids preserve most of their characteristics even during extended proliferation and passage (63)