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After completion of the isoelectric focusing, the strip was equilibrated in the equilibration solution as described by Barraclough [37] and placed on a polyacrylamide gel for SDS-PAGE with a Protean II unit (Bio-Rad, USA) at a constant voltage (300 V)
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The standard research protocols for epitalon involve cyclic administration, typically 10 days on followed by extended breaks, which may allow the immune system to recalibrate during off periods
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