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Weight loss Available in NZ = Liraglutide high dose (Saxenda, daily injection) Self-funding needed ($500-600/month) Not available in NZ = Semaglutide (Ozempic, Wegovy) or Tirzepatide (Mounjaro), as of May 2023 Side effects, particularly upper gastrointestinal, are common with GLP-1 agonist initiation
Research suggests that by age 40, our L-Glutathione levels drop by 30% and are typically halved by age 65
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During the drip, patients typically relax in a chair or another comfortable setting while the infusion is administered gradually under supervision
Development of GLP-1MK-801 To safely harness the weight-lowering properties of NMDA receptor antagonism, we developed a targeting approach based on the hypothesis that conjugation of MK-801 to a GLP-1 analogue through a chemically cleavable disulfide linker would enhance the therapeutic potential of NMDA receptor antagonism in appetite-regulating brain regions enriched for GLP-1 receptors, while mitigating the adverse effects related to the non-restricted actions of MK-801
This drug may cause side effects, including nausea/vomiting, diarrhea, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, hypersensitivity reactions, gas, hair loss, GERD, abdominal distension, dizziness, and low blood pressure
